No ovaries required: viable eggs grown in a dish

No ovaries needed: viable eggs grown from mouse stem cells

Growing eggs from basically nothing!!!

cosmosmagazine.com

Scientists have successfully coaxed mouse stem cells to develop into functional eggs in a dish – that then grew into baby mice, according to a study published in Developmental Biology.

This has wide implications for assisted reproductive technologies in the future, because it may provide an alternative to egg donors.

A team of researchers, led by Takashi Yoshino of Kyushu University, Japan, developed culture conditions in a petri dish that imitated ovarian follicles to recreate the process that stem cells normally take to turn into eggs, which resulted in viable eggs. They called the lab-grown cells ‘reconstituted Ovarioids’ (rOvarioids).

Pluripotent stem cells are immature but have the potential to become almost any type of cell under the right conditions. In the ovary, these cells can become oocytes, which eventually turn in to eggs.

Normally, oocytes are encapsulated by ovarian cells in a fluid-filled follicle structure that help the oocyte undergo a round of meiosis (a type of cell division) and become an ovum (an egg that can be fertilised).

Previously, it was hard to grow the oocytes and ova in a petri dish because the ovarian follicles are essential in the process, so the team developed a culture as an “incubator” for the eggs to grow in, outside of the ovary.

The team took stem cells from mature female mice and placed them in the culture. This simulated the normal ovary environment so effectively that the stem cells developed into functional oocytes –rOvarioids – that could later be fertilised via in vitro fertilisation (IVF) and implanted into mice wombs.

Incredibly, 5.2% of the embryos derived from rOvarioids grew into babies after implantation, and all of the babies born via the method grew to adulthood.

This is comparable to the effectiveness of IVF-derived embryo transfer success in people over 43 years of age, but there is no restriction on the amount of eggs available, because lots of rOvarioids can be made.

“This technical breakthrough holds enormous potential for (reproductive) cell research,” says Lin Yang of the Genome Institute of Singapore.

Ying explains that this allows for high-yield IVF entirely without eggs or genetic manipulation.

Reconstitution of follicle structures, including oocytes, entirely from mouse pluripotent stem cells. Illustrations on the left show a schematic overview of reconstitution of both the ovarian filament cells (FOSLCs) and stem cell-derived eggs (PGCLCs) from mouse stem cells. Oocytes in the reconstituted environment gave rise to offspring after fertilization. The right image represents fully grown cumulus-oocyte complexes derived from FOSLCs (red) and PGCLCs (blue). Credit: Yoshino et al.

 

[Dysnomia]

Hm. Interesting. Yesterday I got recommended a video about chicken eggs being incubated in glasses and watched it. Out of the dozen, only one was able to survive full term. Obviously growing in eggs is vastly different from growing in wombs but it was interesting though (the narrator's cheesy tone helped).
https://youtube.com/watch?v=xOLy6J1Sorg
Goes without saying but doesn't matter what creature the zygotes come from, this is incredibly creepy. Pray that God doesn't blink from all this pissing in His eye lately.

I feel stuff like this is inevitable though. Hopefully by the time it's commercially available the trooning out craze will have died down. Because it's the troons that are going to be right at the gate demanding their biological mutant baby. it says here that they are using female mouse stem cells. But we all know where this may be going. Or where troons will expect it too.

If god exists he's a fuck wit and I'm pretty sure even we can do better...

So lets keep playing god and Spit in the eye of nature!

I sometimes wonder if we are just the creation of some mad scientists who ascended to godhood just because they were a little more mad than us.

Can't wait to see what we become gods of. It can only go down hill from here.

 

[VelcroPocket]

Nice idea! using old stem cells to make ova! What? the UV rays and chemicals damaged the DNA? Who cares! Now this 45 yo woman have a tard baby! Her baby!

 

[TowinKarz]

Abortions will be as easy as wiping clean a petri dish.

You just know some virture-signaling feminist will do it, too.

Cultivate 30 potential kids and then ritualistically douse the dish in Clorox, to prove how great abortion is...

I can see this becoming a vanity thing for the rich and idle... here's my designer jeans to prove how rich and hip I am, here's my designer fair-trade coffee maker, to prove how ecologically-friendly and globalist I am, and here's my artificial womb where I create and then abort a kid at the press of a button to prove what a good feminist I am.

Or maybe I just woke up extra-cynical today?

 

[Billy Beer]

You just know some virture-signaling feminist will do it, too.

Cultivate 30 potential kids and then ritualistically douse the dish in Clorox, to prove how great abortion is...

I can see this becoming a vanity thing for the rich and idle... here's my designer jeans to prove how rich and hip I am, here's my designer fair-trade coffee maker, to prove how ecologically-friendly and globalist I am, and here's my artificial womb where I create and then abort a kid at the press of a button to prove what a good feminist I am.

Or maybe I just woke up extra-cynical today?

I've been thinking about this technology and i don't think it will be used for human children.

With all the talk of lab grown meat, why not use this to grow eggs of the chicken variety, animal stem cells to grow various parts of cows, sheep and pigs

 

[AnotherPleb]

I've been thinking about this technology and i don't think it will be used for human children.

With all the talk of lab grown meat, why not use this to grow eggs of the chicken variety, animal stem cells to grow various parts of cows, sheep and pigs

Troons say hello.

 

[Billy Beer]

Troons say hello.

Ideologically they can say what they want. Follow the money. Fake meat will be a bigger industry and an even bigger virtue signal than lopping ya knackers off

 

[The Lawgiver]

Every day we inch closer to the dystopian hellfuture warned about in various scifi stories of the last several decades.
Every day we inch closer to a "This world has lost it's dignity, Luigi." scenario.
Pray for our future generations.