Devin in HD just seems like an AnyAustin clone. He has a narrow-minded view of the quest with the whole 'ghouls are people too' schtick but ultimately I found it to be a relatively mundane interpretation of Tenpenny Tower.
This response video by Dez I felt weird about because he goes on and on about how humans and ghouls can't live together because ghouls are super diseased and the people of Tenpenny Tower will get sick living with Roy's crew. This is despite multiple communities in the franchise containing both human and ghoul citizens living together and having no health issues. He says that ghouls got kicked out of Diamond City because of this by the mayor and a ghoul had randomly gone feral. Problem is the mayor was McDonough, who might've been an institute synth at the time. Hancock says his brother was acting super weird at the time, so I assume McDonough was replaced by this point. As for the ghoul randomly going feral, that's just another Bethesda fuck up as I see it, since they typically only go feral from constant radiation exposure and there's no radiation in Diamond City. Bethesda love retconning stuff to further plotlines. Dez does bring up Wiseman in Fallout 4 mentioning ghoul decay, but Wiseman is just one guy and can't know everything.
Tenpenny Tower as a quest has aged very funny though. At the time, Emil assumed he was just being clever by putting a subversive twist ending in. Now in 2026, well, let's just say the quest has never been more relevant.